COURSE OBJECTIVES:
• To recognise the fundamental theories of reaction rates, mechanism of chain reactions
• To develop a deeper knowledge in chemical kinetics, mechanism of heterogeneous catalysis, enzyme catalysis and mechanisms.
LEARNING OUTCOMES:
After the completion of the course, students will be able to –
- Understand the theories of reaction rates and different types of reactions.
- Understand acid base catalysis and mechanisms.
SYLLABUS
Module I – Theories of reaction rates:
Lesson 1: Collision theory,kinetic theory of collisions, steric factor, potential energy surfaces.
Lesson 2 : Conventional transition state theory
Lesson 3 : Thermodynamic formulation of the reaction rate-Eyring equation. Significance of ΔG≠, ΔH≠ and ΔS≠, volume of activation.
Lesson 4 : Comparison of the ACT & Collision theory
Lesson 5 :Effect of pressure and volume on velocity of gas reactions.
Module II – Unimolecular reactions
Lesson 1 – Lindemann- Hinshelwood mechanism
Lesson 2 – RRKM theory
Module III – Chain reactions
Lesson 1: Chain initiation processes, steady state treatment
Lesson 2 : kinetics of H2-Cl2 and H2-Br2 reactions
Lesson 3 : Rice-Herzfeld mechanism for decomposition of ethane and acetaldehyde
Lesson 4 : Goldfingr-Letort-Niclause rules
Lesson 5 : branching chains reactions – Semenov-Hinshelwood mechanism , upper and lower explosion limits, the H2-O2 reaction
Lesson 6 : kinetics of step growth, free radical, cationic and anionic polymerization reactions.
Module IV : Fast reactions
Lesson 1: Relaxation methods
Lesson 2 : flow and shock methods
Lesson 3: flash photolysis
Lesson 4 : NMR methods
Lesson 5 : ESR methods
Module V : Reactions in solution
Lesson 1: Factors determining reaction rates in solutions, effect of dielectric constant and ionic strength
Lesson 2: cage effect, Bronsted-Bjerrum equation
Lesson 3: primary and secondary kinetic salt effect.
Module VI – Acid base catalysis
Lesson 1: Specific and general catalysis
Lesson 2: Skrabal diagram
Lesson 3 : Bronsted catalysis law
Lesson 4 : prototropic and protolytic, acidity function.
Module VII : Enzyme catalysis
Lesson 1: Michelis-Menten equation, effect of pH and temperature on enzyme catalysis.
Module VIII : Introduction to oscillating chemical reactions
Lesson 1 : auto-catalysis
Lesson 2 : the Lotka-Volterra mechanism
Lesson 3 : the brusselator, the oreganator, bistability.
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Introduction
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Module 1: theories of reaction rates
- Lesson 1: Collision theory,kinetic theory of collisions, steric factor, potential energy surfaces.
- Lesson 2 : Conventional transition state theory
- Lesson 3 : Thermodynamic formulation of the reaction rate-Eyring equation. Significance of ΔG≠, ΔH≠ and ΔS≠, volume of activation.
- Lesson 4 : Comparison of the ACT & Collision theory
- Lesson 5 :Effect of pressure and volume on velocity of gas reactions.
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Module 2: Unimolecular reactions
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Module 3 : Chain reactions
- Lesson 1: Chain initiation processes, steady state treatment
- Lesson 2 : kinetics of H2-Cl2 and H2-Br2 reactions
- Lesson 3 : Rice-Herzfeld mechanism for decomposition of ethane and acetaldehyde
- Lesson 4 : Goldfingr-Letort-Niclause rules
- Lesson 5 : branching chains reactions – Semenov-Hinshelwood mechanism ,upper and lower explosion limits, the H2-O2 reaction
- Lesson 6 : kinetics of step growth, free radical, cationic and anionic polymerization reactions.
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Module 4 : fast reactions
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Module 5 : reactions in solutions
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Module 6: Acid base catalysis
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Module 7 : Enzyme catalysis
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Module 8 : Introduction to oscillating chemical reactions
